An analysis of common symptoms and treatment methods in patients infected with the bubonic plague

Septicaemic plague - there is usually no evidence of lymph node involvement. Other types of Y. Unlike bubonic plague, pneumonic plague is highly contagious among humans bubonic plague is not contagious among humansand mortality is even higher. If cultures yield negative results, and plague is still suspected, serologic testing is possible to confirm the diagnosis.

Maintain surveillance of natural foci by bacteriologic testing of sick or dead wild rodents and by serologic studies of wild carnivore and outdoor ranging dog and cat populations in order to define areas of plague activity.

Swelling of lymph nodes These usually follow an incubation period of days[ 4 ]. If nonburrowing wild rodents are involved, insecticide bait stations can be used. There may also be necrosis of blood vessels with purpura and gangrene.

A few sporadic cases will likely be missed or at least not attributed to a deliberate bioterrorist act.

Antibiotic Treatment of Experimental Pneumonic Plague in Mice

Education of persons likely to be involved in handling carcasses that may be infected with plague to wear appropriate clothing eg gloves.

Experiments included various delivery methods, vacuum drying, sizing the bacterium, developing strains resistant to antibiotics, combining the bacterium with other diseases such as diphtheriaand genetic engineering.

Sponsored link What is the bubonic plague? The purpose of these studies was to investigate the efficacy of a number of antibiotics, all with demonstrated in vitro efficacy against Y.

Preparation of the Y. After the third booster dose, the intervals can be extended to every 1 to 2 years. These airborne insects love to inhabit various animals such as rodents, goats, stray dogs, squirrels, rabbits and coyotes. Fever Feeling generally weak and achy malaise Headache Blister or infection at the site of a flea bite Red or purple rash on top of the enlarged lymph nodes Bubonic plague can evolve into septicemic or pneumonic plague; these people will look even sicker, with symptoms of weakness, confusion, abdominal pain, cough, chest pain, and presence of blood-tinged sputum.

Gentamicin and tetracyclines have been used with success 112345while trimethoprim-sulfamethoxazole has also been employed, with both success 32 and disappointing results 6.

This bacterium is carried by a certain type of flea, commonly known as a rat flea, which infects humans and animals. The earlier a patient seeks medical care and receives treatment that is appropriate for plague, the better their chances are of a full recovery.

Culture is possible from sputum of very ill pneumonic patients; however, blood is usually culture-positive at this time as well. However, pneumonic plague also occurs, either as a result of primary inhalation of aerosolized organisms from close contact with pneumonic plague in a human or animal or secondary to metastatic infection associated with bacteremic spread from a primary bubonic focus.

Blood smears taken from suspected bubonic plague patients early in the course of illness are usually negative for bacteria by microscopic examination but may be positive by culture.

One hundred microliters from each dilution tube was spread on SBAP, in duplicate, and CFU were counted after incubation at room temperature for 48 h.

Epidemiology of plague Distribution of plague infected animals Globally about cases are reported a year. Signs and Symptoms The typical symptoms of bubonic plague infection are large, swollen, tender lymph nodes called buboes. Use gloves, face masks and gowns if available.

The mainstay of treatment is antibiotics. Hikers, particularly in endemic areas. The mortality and contagibility of pneumonic plague is very high.

Besides streptomycin, there are a limited number of antibiotics with demonstrated efficacy for the treatment of plague in humans. Plague bacteria secrete several toxinsone of which is known to cause beta-adrenergic blockade. Infection was induced by inhalation of aerosolized Yersinia pestis organisms.

Resources for Clinicians

You will be started on antibiotics, and people in close contact with you may also be started on antibiotics to prevent against disease, though there is little risk of person-to-person transmission with bubonic plague.

Abstract A mouse model was developed to evaluate the efficacy of antibiotic treatment of pneumonic plague; streptomycin was compared to antibiotics with which there is little or no clinical experience.

The initial signs are indistinguishable from several other respiratory illnesses; they include headache, weakness and spitting or vomiting of blood. All are highly effective if used early within hours after onset of pneumonic plague. Children can be treated with streptomycin or gentamicin.

The plates were then incubated for 2 days at room temperature, and the colonies were counted. A known flea bite or the presence of a bubo may help a doctor to consider plague as a cause of the illness. Chloramphenicol - may be better in plague meningitis as it crosses the blood brain barrier, however this has not been confirmed and the drug is associated with toxicity eg bone marrow failure.

Live attenuated vaccines are used in some countries, but may produce more adverse reactions and there is no evidence that they are more protective.

Today, most human cases of the plague occur in Africa though they do appear elsewhere. How to prevent plague Keeping the rodent population under control in your home, workplace, and recreation areas can greatly reduce your risk of getting the bacteria that causes plague.

The Plague

Those who have been in household or face to face contact with patients with pneumonic plague should be provided chemoprophylaxis see 9B5below and placed under surveillance for 7 days; those who refuse chemoprophylaxis should be maintained in strict isolation with careful surveillance for 7 days.Bubonic plague treatment.

primarily involves taking antibiotics to kill the bacteria as well as certain medications to resolve the associated symptoms. Patients should expect to be quarantined during the course of the treatment to prevent the disease from spreading to other people.

How to Prevent being infected by bubonic plague. Bubonic Plague Essay Examples. 70 total results. The Features of the Black Plague and Its Effects. words. An Analysis of Common Symptoms and Treatment Methods in Patients Infected with the Bubonic Plague.

Plague (disease)

words. 1 page. The Contagious Disease of the Bubonic Plague. 1, words. Images of Plague, Bubonic. Close Video. Humans can get bubonic plague from the bite of an infected flea, Signs and Symptoms. The typical symptoms of bubonic plague infection are large, swollen, tender lymph nodes called buboes.

These usually occur in the neck, armpit, and groin. METHODS OF CONTROL.

Diagnosis and Treatment

Immunization of visitors to epidemic localities and of laboratory and field workers handling plague bacilli or infected animals is justifiable but should not be relied upon as the sole preventive measure. For patients.

If infected, treatment is with antibiotics and supportive care. Experiments included various delivery methods, vacuum drying, sizing the bacterium, information on bioterrorism preparedness and response regarding plague; Symptoms, causes, pictures of.

treatment of bubonic or septicaemic plague and is the drug of choice for treatment of patients with Y. pestis invasion of tissue spaces into which other drugs pass poorly or not at all (such as plague meningitis, pleuritis.

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An analysis of common symptoms and treatment methods in patients infected with the bubonic plague
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